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23&me Results

When I did 23&me I was most excited to learn about my ancestry. My 23&me results were somewhat disappointing. Both sides of my family claim some Native American ancestors, but 23&me says that I am 98.4% European and of that 79% Northern European with the rest being non-specific European. I am only 0.8% Native American, which is enough to show that there might be something in my past, but not as recent as some family members would like to say.  I have a small amount of German/French ancestry (3.4%), but the cool part about that is that it is all located together on one of my two second chromosomes. So I have almost an entire chromosome that is from German/French ancestry. The 0.8% Native American is also together in one piece indicating that it came from one place, which is pretty cool. I could be possible that the genes from my Native American ancestor were lost during crossing over events in my parents, grandparents, great-grandparents, etc. So there still could be more Native American ancestry than what shows up. So I now know a lot more about my extended heritage, but nothing ground breaking or exciting was found.

Probably one of the coolest ancestry things I found is that I am 3% Neanderthal putting me into the 88th percentile. That is pretty cool, and makes sense with my Northern European ancestry.

When it came to my health results, there was only one thing that was major for me: I have two copies of the APOE ε4 variant. This increases my risk for Alzheimer's to 39.9%. If you have a family history, you can assume that this is correct or even raised. My grandmother and two of her siblings are currently suffering from the disease. My risk factor for this is extremely high, and this is pretty scary. I'm not really sure what all there is that I can do about this. There are no confirmed ways to prevent it. I'm not guaranteed to get the disease, but with my family history, I have to admit that it is extremely likely.

There really wasn't anything else significant that I found. It knew my hair color, and eye color. One other thing I found interesting is that I am "likely a sprinter." I've never been much for exercising, but running has always been my preferred thing to do if I am going to exercise regularly. Maybe I should start running more often.



3 thoughts on “23&me Results

  1. rtburbach

    I spoke to soon about my 3% Neanderthal DNA. It's weird that yours say 88th percentile and mine said 94th. I wonder why they are different...?

    I didn't even really know I had a family history of Alzheimer's until this test (I thought the members who had it were related by marriage somehow). I freaked out and didn't want to talk about it at first. It sucks, but I'm glad to not be alone in our class with this result.

  2. Christopher Lynn

    We should have had everyone display their supposed genetic talents on the last day. Maybe I should have you sprint down the hall as part of your final? Anyway, the Alzheimer's risk is not funny. I'm sorry that you learned that. Do you wish you didn't? As for your Native American blood, I think the "we have 3.125% Cherokee blood" on each side is white American folklore. It's like the urban legend of every family. But what does that mean, really? My family's story is that someone married a Cherokee or half-Cherokee woman 3-4 generations back. Maybe they did & maybe they didn't, but if they did, how "Cherokee" were her genes? I sort of wish we had another semester together so we could spend more time just investigating & discussing these details. I think writing a paper about our 23&me data would have been a really good way to digest it all.

  3. peadams

    I don't wish that I didn't know about the Alzheimer's risk. I already knew I was probably going to be high risk. It's a little depressing, but it's also just part of life, and way in the future. However, in Integrated Genomics with Laura Reed we discussed the pros and cons of knowing these things. One of which is how accurate are these results, which is part of what the FDA cares about. It's a tricky subject. I am in a position where I understand and appreciate genetic information, but should everyday people have this information?

    I wish we had had more time to talk about our results in class.

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